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Takeshi Iwatsubo Selected Research

Carotid Stenosis (Carotid Artery Stenosis)

1/2019Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight.

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Takeshi Iwatsubo Research Topics

Disease

117Alzheimer Disease (Alzheimer's Disease)
05/2024 - 04/2002
43Parkinson Disease (Parkinson's Disease)
03/2024 - 05/2002
27Dementia (Dementias)
11/2023 - 05/2002
22Amyloid Plaque
12/2023 - 04/2002
17Neurodegenerative Diseases (Neurodegenerative Disease)
11/2021 - 02/2002
17Synucleinopathies
03/2012 - 02/2002
15Cognitive Dysfunction
02/2024 - 11/2002
10Multiple System Atrophy
10/2007 - 05/2002
6Tauopathies
05/2022 - 08/2003
5Neoplasms (Cancer)
03/2024 - 06/2004
5Atrophy
02/2024 - 11/2008
4Frontotemporal Dementia (Semantic Dementia)
11/2021 - 04/2004
3Disease Progression
01/2024 - 01/2019
3Edema (Dropsy)
09/2023 - 01/2014
3COVID-19
09/2022 - 09/2021
3Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
05/2022 - 04/2002
3Parkinsonian Disorders (Parkinsonism)
05/2022 - 04/2004
3Sarcoma (Soft Tissue Sarcoma)
01/2022 - 01/2018
3Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
01/2022 - 04/2006
3Down Syndrome (Down's Syndrome)
10/2018 - 07/2004
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2018 - 04/2015
3Lewy Body Disease (Lewy Body Dementia)
11/2007 - 08/2003
2Ataxia (Dyssynergia)
03/2024 - 11/2005
2Inflammation (Inflammations)
11/2023 - 12/2019
2Insulin Resistance
11/2021 - 12/2019
2TDP-43 Proteinopathies
11/2021 - 11/2013
2Gliosis
12/2020 - 01/2014
2Crohn Disease (Crohn's Disease)
01/2018 - 01/2016
2Infections
07/2013 - 10/2004
1Paraneoplastic Cerebellar Degeneration
03/2024
1Hemosiderosis
09/2023
1Body Weight (Weight, Body)
01/2023
1Pathologic Processes
01/2023
1Neuroinflammatory Diseases
12/2021
1Type 2 Diabetes Mellitus (MODY)
11/2021

Drug/Important Bio-Agent (IBA)

63Amyloid (Amyloid Fibrils)IBA
11/2023 - 04/2002
37Proteins (Proteins, Gene)FDA Link
02/2024 - 02/2002
36alpha-SynucleinIBA
11/2010 - 02/2002
29Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2016 - 04/2002
26Peptides (Polypeptides)IBA
07/2022 - 04/2002
24Amyloid beta-PeptidesIBA
01/2023 - 11/2002
17Biomarkers (Surrogate Marker)IBA
02/2024 - 11/2002
15Phosphotransferases (Kinase)IBA
03/2024 - 11/2006
13Leucine (L-Leucine)FDA Link
01/2024 - 11/2006
9Apolipoproteins E (ApoE)IBA
04/2024 - 01/2006
8Peptide Hydrolases (Proteases)FDA Link
01/2016 - 09/2004
8PresenilinsIBA
01/2014 - 04/2002
7Presenilin-1IBA
01/2016 - 11/2002
6Donepezil (Aricept)FDA LinkGeneric
02/2024 - 01/2021
6AntibodiesIBA
09/2009 - 12/2002
5ApolipoproteinsIBA
04/2024 - 01/2006
5SynucleinsIBA
02/2024 - 04/2008
5Flavin-Adenine Dinucleotide (FAD)IBA
03/2010 - 03/2003
4Monoclonal AntibodiesIBA
09/2023 - 04/2002
4CalciumIBA
01/2019 - 06/2008
4sarkosylIBA
02/2016 - 04/2002
4CollagenIBA
01/2014 - 04/2002
3Insulin (Novolin)FDA Link
10/2023 - 12/2019
3LipidsIBA
03/2022 - 05/2005
3Protein Kinases (Protein Kinase)IBA
11/2020 - 02/2007
3N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamideIBA
01/2015 - 07/2013
3Amyloid beta-Protein Precursor (Amyloid Protein Precursor)IBA
10/2009 - 02/2007
3Serine (L-Serine)FDA Link
03/2009 - 10/2003
2rab GTP-Binding ProteinsIBA
03/2024 - 11/2020
2solanezumabIBA
09/2023 - 01/2014
2CytokinesIBA
12/2021 - 05/2004
2thioflavin TIBA
12/2020 - 07/2004
2Trans-Activators (Trans-Acting Factor)IBA
01/2019 - 04/2015
2CholesterolIBA
10/2018 - 05/2005
2tau Proteins (tau Protein)IBA
11/2017 - 03/2005
2GTP-Binding Proteins (G-Protein)IBA
01/2013 - 02/2007
2Inositol 1,4,5-Trisphosphate Receptors (Inositol Triphosphate Receptor)IBA
03/2010 - 06/2008
2Membrane Proteins (Integral Membrane Proteins)IBA
10/2009 - 04/2002
2Codon (Codons)IBA
11/2007 - 11/2002
2Gamma Secretase Inhibitors and ModulatorsIBA
06/2006 - 06/2004
2Protein Isoforms (Isoforms)IBA
04/2006 - 04/2004
2Endopeptidase K (Proteinase K)IBA
11/2002 - 05/2002
1anti-Yo autoantibodiesIBA
03/2024
1Apolipoprotein E4IBA
12/2023
1Insulin Receptor Substrate ProteinsIBA
10/2023
1Immunoglobulin G (IgG)IBA
01/2023
1lecanemabIBA
01/2023
1FilaminsIBA
05/2022
1Microfilament Proteins (Actin Binding Proteins)IBA
05/2022
1benzamideIBA
05/2022
1BenzodiazepinesIBA
05/2022
1Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA
05/2022
1Anticonvulsants (Antiepileptic Drugs)IBA
05/2022
1phenothiazineIBA
05/2022
1Antipsychotic Agents (Antipsychotics)IBA
05/2022
1Monomeric GTP-Binding ProteinsIBA
01/2022
1RNA-Binding Proteins (RNA-Binding Protein)IBA
01/2022
1Casein Kinases (Casein Kinase)IBA
01/2022
1Antisense OligonucleotidesIBA
12/2021
1Insulin ReceptorIBA
11/2021
1Long Noncoding RNAIBA
11/2021
1BNT162 VaccineIBA
10/2021

Therapy/Procedure

18Therapeutics
05/2024 - 06/2004
3Activities of Daily Living (ADL)
01/2023 - 07/2013
1Long-Term Care
09/2022